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In 2020, Lei Sun et al

Though there is not a single specific serum or plasma biomarker for ALS, higher levels of serum neurofilament light chain (NfL), a neuron-specific marker of axonal degeneration, have been found to differentiate ALS from disease mimics, such as inflammatory demyelinating polyneuropathy or structural polyradiculopathy [78], and correlates with rate of progression in ALS as well as disease severity [79]

The results (Zhu et al., 2019) demonstrated that WED alleviates doxorubicin-induced inflammation and OS damage to podocytes via the IK/IB/NF-B pathway