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Metformin, a medication for individuals with type 2 diabetes mellitus, was found to decrease vitamin B 12 absorption possibly by tying up free calcium required for absorption of the IF-B 12 complex (143)

Gut microbiota The gut-brain axis is a pivotal area of interest in studying DPN

Therapeutic Dosing Strategies There are two main ways to take vitamin B12: maintenance and therapeutic dosing

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