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Second, the mechanism by which different GRKs polymorphisms affect enzymatic activity remains still unknown, which may be related with the crystal structure of GRKs polymorphisms

10.1016/j.freeradbiomed.2021.10.011 9 ChenQ.ZhangH.YangY.ZhangS.WangJ.ZhangD.et al (2022)

Chen GM, Chen C, Das RK, Gao P, Chen CH, Bandyopadhyay S, et al

These findings support the clinical utility of AID systems in routine care and reinforce the potential of GRI as an additional tool for individualized treatment assessment in T1D