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Gut microbiota-derived 3-hydroxybutyrate blocks GPR43-mediated IL6 signaling to ameliorate radiation proctopathy

Species verification PCR amplification was performed using ITS2 forward primer (5-TGTGTCGATGAAGAGCGCAG) and ITS2 reverse primer (5-TGGTTAGTTTCTTTTCCTCCGC), as described previously (Morphew et al ., Reference Morphew, Eccleston, Wilkinson, McGarry, Perally, Prescott, Ward, Williams, Paterson, Raman and Ravikumar2012)

This promises to reveal the conditions under which plasticity in the visual pathway can be maintained or even induced: this would open up the possibility whereby modulation of "molecular switches" with specific drugs could allow or facilitate the regeneration of damaged pathways

Improvements were seen not only in facial function, but also in nerve conduction studies, providing physiological support for its effect