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It increases the risk for multiple metabolic complications including type 2 diabetes (T2D), metabolic-dysfunction associated steatotic liver disease (MASLD, previously known as non-alcoholic fatty liver disease), cardiovascular disease as well as many mechanical complications such as osteoarthritis and obstructive sleep apnoea (OSA) [3]

Preclinical studies suggest TB-500 may help support: Cell migration Healthy inflammation modulation Soft-tissue and joint wellness General athletic recovery TB-500 is also considered experimental for horses and should not be used without veterinary oversight

It was shown to reduce hepatic lipid accumulation and improve inflammation and fibrosis [180]

The amylin pathway represents a fundamentally different approach than GLP-1 agonists, making it complementary rather than redundant