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A consistent model goes with ligation leading to vessel injury, exposure of tissue factors, stasis, thrombosis, hemodynamic changes, arterial hypotension, and in particular, venous hypertension, which approximates values over 20 mm Hg in the inferior caval vein, 101 thereby being roughly four times higher than those in normal rats

Generally, doses range from 100 to 200 micrograms (mcg) per injection

However, theres no difference in the time of day youre injecting

Any use should be discussed with a qualified healthcare professional who can evaluate the individuals health history, goals, current medications, and potential risks