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doi: 10.3390/ijms21239191 95 PandyaCPillaiPNampoothiriLPBhattNGuptaSGuptaS

The novel oral BET-CBP/p300 dual inhibitor NEO2734 is highly effective in eradicating acute myeloid leukemia blasts and stem/progenitor cells

Small interfering RNA (siRNA) cell transfection M229 cells were transiently transfected with siRNA according to the manufacturers protocol by Lipofectamine RNAiMAX (Life Technologies, Carlsbad, CA, USA) with on-target SMARTpool control siRNA (D-001810-10-20) and siRNA targeting human JARID1A (KDM5A) (L-003297-02-0005), human JARID1B (KDM5B) (L-003297-02-0005), and human JARID1C (KDM5C) (L-010097-01-0005) purchased from Dharmacon (Lafayette, CO, USA)

Table 6 reveals their compound name, plant species, Chinese Pinyin, and the traditional function of Traditional Chinese Medicine (TCM) (Fig