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Molecules with an unpaired electron are reactive and look for another molecule with an unpaired electron to bind to

However, maintenance had a favorable impact on DFS, and among the strategies, the combination of ATRA plus chemotherapy seemed to be superior to the use of ATRA alone.49 In the post-ATO era for the initial treatment of APL, maintenance seems to have lost its role, mainly in low- and intermediate-risk groups, as evidenced by the APL0406 and AML17 trials

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Clinical trials suggest melatonin supplementation can reduce fibromyalgia impact and anxiety, improve sleep, and decrease tenderness