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10.1046/j.1365-2125.2003.01858.x Br

& Whitehouse, M

The increase is dose-dependent, typically stabilizes over time, and does not escalate with long-term use

Similarly, DSF-Cu induced significant mitochondrial morphological damage, hindered energy metabolism, elevated ROS generation, caused DNA double-strand breaks, and expedited ferroptosis in experimental models of hepatocellular carcinoma (HCC) cells, according to Xueying Ren et al