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In addition to their physicochemical properties, the dosage, exposure time and environmental settings also influence the activity of AuNPs

Particularly, the highly reactive 4-OH group on the catechol moiety was selectively blocked by DNBS

Segal AW (2005) How neutrophils kill microbes

HO-1 facilitates the breakdown of heme, resulting in the release of significant quantities of reactive iron ions, which then promote the Fenton reaction, ultimately producing lipid peroxides and causing ferroptosis in osteoblasts ( Figure 3 ) (124, 136)