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Methylation plays an essential role in controlling depression by simultaneously increasing the levels of several neurotransmitters that are deficient in depressed patients

J Clin Epidemiol

FIGURE 1 Intragastric administration of GRP (172 mg/kg body weight) to germ-free and human microbiota-associated (HMA) mice led to the excretion of approximately 30% unchanged GRP in the urine of both germ-free and HMA mice (Budnowski et al., 2015)