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As expected, TRPML1 knockout mice show a decrease in the thickness of myelinated axonal projections and optic nerve thickness, possibly caused by a decrease in blood supply (Grishchuk et al., 2016)

CXCL9 mRNA levels, which did not differ between patients and CTRL at endpoint A, increased in SEV cultures treated with B12 so that its mRNA levels exceeded those of the CTRL at endpoint A

Moreover, CD5/ LNP-FAPCAR 2.2 led to an ~30% reduction in cytokine release compared with that of CD5/ LNP-FAPCAR 2.1 without altering lysis capacity (Fig

Stomach acid changes, intestinal conditions, and autoimmune processes such as pernicious anemia can impair B12 uptake