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798 This mechanism restores mitochondrial targeting sequence pre-processing and alleviates feedback inhibition of mitochondrial processing peptidase activity in fibroblasts from PITRM1-deficient patients, improving Frataxin maturation and mitochondrial function

The pharmacokinetic reasoning supports this (bypassing gut bacteria), but head-to-head comparisons of TMAO levels between routes have not been conducted in the context of compounded tirzepatide