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Populations at a higher risk of vitamin B12 deficiency include people who are vegetarian or vegan, exclusively breastfed infants of vegan women, older adults, those with gastrointestinal disorders or who have had gastrointestinal surgery, and people with an autoimmune condition known as pernicious anemia

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[23], the risk of developing vitamin B12 deficiency was significantly correlated with the duration of metformin intake, with a ninefold increased risk beyond 10 years and a 4.6-fold increased risk for a treatment duration between 4 years and 10 years

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