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First, the ligand-binding pocket is split into two distinct regions, forming a bifurcated pocket. Within this pocket, a salt bridge between Glu124 3.33 and Arg283 6.55 [superscripts denote the BallesterosWeinstein numbering system (Ballesteros and Weinstein, 1995)] divides the ligand-binding pocket into two cavities: a relatively large Cavity I and a smaller Cavity II (Figure 2B)

It not only exerts a ferroptotic effect on tumour cell lines but also exerts an antiferroptotic effect on I/R-induced cell damage

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A growing number of people are exploring GLP-1 medications for weight loss or as part of a broader effort to improve metabolic health, stabilize energy, and prevent long-term issues like diabetes or cardiovascular disease