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Eligibility criteria Studies were included if they met the following criteria Population Human studies in individuals with fibromyalgia or preclinical models relevant to oxidative stress, mitochondrial dysfunction, or redox-modulating interventions

Tan EK, Chan DK, Ng PW, Woo J, Teo YY, Tang K, et al

Furthermore, BCAAs can be used as a nitrogen source for the synthesis of glutamic acid and glutamine in the muscle and brain [57], which seems to explain why BCAAs-containing peptides were down, while glutamine-containing peptides were up

Oxidative stress plays a key role in the development and progression of cancer, and excess free radicals can damage DNA, leading to genetic mutations and carcinogenesis