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Availability of data and materials The dataset supporting the conclusions of this article is included within the article

RNA isolation and qPCR analysis Total RNA from skin and lungs was isolated by RNeasy Fibrous tissue mini kits (Qiagen, Germantown, MD, 74,704)

These treatments include products you apply on the affected skin, which may contain retinol or retinoid, acid, chemical peels, and laser therapy to remove the topmost skin layer