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Another is that erastin restrains systemic X C activity and causes the depletion of GSH, thereby inactivating the GPX4 enzyme, which then induces ROS formation, selectively inducing ferroptosis in HRASV12 mutant BJeLR cells (Dixon et al., 2012)

Mitochondrial JNK activation triggers autophagy and apoptosis and aggravates myocardial injury following ischemia/reperfusion

G.Ortega-RomeroM.Prez-VzquezF.et al

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