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Common signs include: Fatigue and weakness Neurological changes, such as numbness or tingling in the hands and feet Megaloblastic anemia, characterized by large, abnormal red blood cells Cognitive difficulties, including memory loss and confusion Early detection and treatment of B12 deficiency can make a big difference

Patients often report improved mental clarity, memory, and ability to focus

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Studies have found that high NNMT expression promotes the release of inflammatory factors in adipose tissue, and NNMTi can effectively alleviate adipose inflammation and improve the microenvironment by inhibiting NNMT