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[ 88 , 94 , 472 , 474 , 475 ] Keap1, the most validated target for NRF2 activation, is a redox sensor containing several cysteine residues, whose oxidation or modification compromises either dimeric structure formation or combination to ubiquitin ligase, resulting in NRF2 protein release and nuclear import

is defined as a proportionality constant that relates the total amount of drug present in the body at a specific time to the concentration of the drug measured in the plasma

Heat stress decreases testicular germ cell proliferation and increases apoptosis in short term: an immunohistochemical and ultrastructural study

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