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Glutathione IV is the most studied option for gradual skin tone evening

doi: 10.3390/nu8080513 85

Am J Bioinf Res 3:6271 Silviya AE, Kavitha G, Kutty KN, PK KN (2015) Insilico modeling of chitosan as a drug delivery system

The polymer backbone covalently integrates an L-buthionine sulfoximine prodrug to inhibit glutathione biosynthesis, and the nanoparticle matrix encapsulates an elesclomol-copper complex to promote intratumoral copper accumulation