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37 The main reason was that the mice used in Wendels studies were kept on a vitamin E-deficient diet high in PUFAs, which made them highly susceptible to LPO

Moreover, LAG3 was mainly expressed in NK cells, which indicated that combined knockdown of SLC25A39 in CRC cells and chimeric antigen receptor NK-cells immunotherapy targeted to LAG3 might also be an effective strategy in CRC immunotherapy

10.1016/j.neuro.2014.12.002 109 KabirajP.ValenzuelaC

Studies have indicated that IF can improve metabolic health through several mechanisms, including enhanced insulin sensitivity, reduced blood pressure, and improved lipid profiles (2, 3)