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ileum 0.24 0.04 vs

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Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo Cancer Res 1993 53 : 10231026 Lvay G, Bodell WJ

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In the context of SSMD, ensuring that scientists have identified and can agree on the appropriate ortholog to human GPX4 for manipulation is critical, and as a selenoprotein GPX4 presents further challenges across other species

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Insights from these assays mitigate the risk of late-stage conflicting data, drug candidates being wrongly abandoned as toxic or mistakenly classified as safe

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