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Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferator-activated receptor-gamma coactivator-1 alpha, estrogen-related receptor-alpha, and mitofusin 2

Metabolic disorders of the immune system in the TME are expected to improve the efficacy of metabolism-targeted anticancer strategies [287, 288]

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After 24 h, the medium was replaced with 5 M dye (1 mL) in phenol red-free medium followed by incubation for 15 min, and images were acquired at200 magnification under a fluorescence microscope (Leica Microsystems, Wetzlar, Germany)