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BCKAs can be metabolized by BCKDH to branched-chain acyl-CoA, and blocking this step causes serious metabolic disorders, such as maple syrup urine disease (Xu et al., 2020) and propionic academia (Chen et al., 2007) or acetylation modification (Campbell and Wellen, BCAAs are important nutrient sources (Kamphorst et al., 2015)

Its scientific name, Glycyl-L-Histidyl-L-Lysine, refers to a tripeptide structure combined with copper ions

J Thorac Oncol 8(2):238-45, 2013

, 22 , 4104-4110, doi: Strohkamp, S., Gemoll, T., Humborg, S., Hartwig, S., Lehr, S., Freitag-Wolf, S., Becker, S., Franzn, B., Pries, R., Wollenberg, B., Roblick, U