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10.1371/journal.pone.0093258 139 YingX.GaoK.LuoZ.RenY.ShenC.ZhangH.et al (2025)

This rapid proliferation is primarily driven by the pro-inflammatory cytokines secreted by Th1 and Th17 cells, particularly IL-17 and IL-22, which promote keratinocyte proliferation and inhibit their normal differentiation (Ortiz-Lopez et al