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Step 7: Visually inspect the reconstituted solution for clarity, absence of particulates, and complete solubilization before use

The HMOX1 inhibitor zinc protoporphyrin IX (ZnPP) prevents erastin-induced ferroptotic cell death, whereas the HMOX1 inducer hemin accelerates erastin-induced ferroptosis in HT1080 cells (Sun et al., 2016b)

doi: 10.3389/fphar.2021.718147 Received 09 June 2021 Accepted 17 November 2021 Published 13 December 2021 Volume 12 - 2021 Edited by Fan Jiang, Shandong University, China Reviewed by Dechang Chen, Shanghai Jiao Tong University, China Ying Li, Xian Jiaotong University, China Updates Copyright 2021 Tepes, Gojkovic, Krezic, Zizek, Vranes, Madzar, Santak, Batelja, Milavic, Sikiric, Kocman, Simonji, Samara, Knezevic, Barisic, Lovric, Strbe, Kokot, Sjekavica, Kolak, Skrtic, Seiwerth, Boban Blagaic and Sikiric