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Studies also found upregulation of specific growth factors at injury sites in BPC-157-treated animals factors known to drive collagen production and fiber alignment

The quality and speed of these processes depend heavily on cellular energy production, nutritional availability, and the presence of specific molecular signals that coordinate healing responses

Nevertheless, it is believed that antiangiogenic monotherapy aiming at single molecule activity is insufficient to combat the myriad of angiogenic factors produced by cancer cells and its microenvironment and this would explain, at least partly, the modest effect of anti VEGF strategies