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Description

Raghu G, Anstrom KJ, King TE Jr, Lasky JA, Martinez FJ

Conducting studies with oral formulations might require more foundational research to establish optimal parameters, adding layers of complexity to experimental design

These modifications protect the peptide from exopeptidase-mediated degradation aminopeptidases at the N-terminus and carboxypeptidases at the C-terminus resulting in substantially improved metabolic stability in biological matrices