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The peptide simply does not have the conformational features required for growth hormone receptor recognition and activation

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Its documented history is unusual among research peptides because it can be read as the pursuit of one narrow scientific question across roughly two decades: whether the fat-related actions of the growth hormone molecule can be uncoupled from its growth-promoting and glucose-related actions

Much evidence supports a complex role for perilipin proteins in regulating both basal and stimulated adipocyte lipolysis