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The five components of the immune system, the epithelium, innate immune cells, T cells, B cells, and effector cells (mast cells, eosinophils, and basophils), can either promote tolerance to food antigens or sensitization, leading to allergic manifestations

They had observed that 10 mol/L curcumin, when incubated with a vincristine-resistant gastric carcinoma cell line, could downregulate the expression of P-gp, in addition to promoting caspase-3 activity in MDR cells [236]

Based on the aforementioned findings, we speculation that this mechanism may be crucial in explaining how Vit A supplementation enhances the quality of cryopreserved bucks semen

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