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Concurrently, metabolic signals such as the arginine-spermine axis associated with tumor cells can induce the activation and phenotypic transformation of immunosuppressive cells, accelerating the degree of immune suppression in the microenvironment

Among these 83.3% had mild/moderate steatosis, 16.7% diabetes, 33.3% arterial hypertension

10.1016/j.arr.2019.100942 77 FarB