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Vigliani, E.C., Pernis, B., Monaco, L., A study of the action of quartz particles on macrophages in vitro

Research has demonstrated that the concurrent application of immune checkpoint inhibitors including PD-1 inhibitor and CTLA-4 inhibitor can block immune checkpoint signals, relieve the inhibitory effect of DTP cells upon T cells, significantly enhance T cell activity, and consequently enhance the lethality of CAR-T cells against DTP cells (140143)

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We then tested whether this motif was important for ORF3a function in autophagy and its interaction with VPS39