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10.2174/0929867324666170920155439 68 JelinekA.HeyderL.DaudeM.PlessnerM.KrippnerS.GrosseR.et al (2018)

We previously demonstrated that RMC exhibits a hot immune-inflamed phenotype characterized by upregulation of immune checkpoints such as cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1) in the tumor immune microenvironment 10