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Disrupted glutathione homeostasis in the pathogenesis of TTR-V30M amyloidosis

In normal appearing white matter in post mortem brain tissue, MGO-derived AGEs and the microglial marker allograft inflammatory factor 1 (Aif1/Iba1) were not co-localized [112]

Blume CA, Boni CC, Casagrande DS, Rizzolli J, Padoin AV, Mottin CC

this is cell and animal evidence, not a supervised human therapy, and individual outcomes are unknown because controlled human muscle-growth studies do not exist