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In contrast, mTOR deficiency leads to hyperactivation of the TGF-Smad3 pathway and promotes Treg cell formation [155]

Zhang et al., 2017

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The transcriptional levels of Cldn1 and Cldn7 were evidently higher in the EpCAM +/ + DSS group than the WT, WT + DSS, and EpCAM +/ groups ( p 0.001 ) (Figure 3A)