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Changes in gut viral and bacterial species correlate with altered 1,2-diacylglyceride levels and structure in the prefrontal cortex in a depression-like non-human primate model

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Biomed Eng Lett (2017) 7(2):5969

In a mouse model of cerebral ischemia, HCA2 activation by BHB promotes a neuroprotective phenotype of macrophages to produce prostaglandin D2, which exerts neuroprotective effects, suggesting a potential immunomodulatory mechanism that may be relevant in inflammatory contexts [45]