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Vitamin B12 is an essential vitamin that plays an important role in cell reproduction, blood formation, metabolism of fat and carbohydrates, and protein synthesis

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Professor Ngs research contributions to AOD-9604 development include: Synthesis and characterization of the modified C-terminal growth hormone fragment with enhanced stability Design of the tyrosine N-terminal modification to improve peptide stability and half-life Preclinical studies demonstrating lipolytic effects in obese animal models Advancement of the peptide through multiple phases of clinical development Investigation of mechanisms underlying beta-3-adrenergic receptor modulation His work established the foundation for understanding peptide-based approaches to metabolic regulation, though clinical translation ultimately proved unsuccessful

[PubMed abstract] Lildballe DL, Fedosov S, Sherliker P, Hin H, Clarke R, Nexo E