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The majority of ingested sucralose is not broken down by the body, so it is noncaloric

In advanced cellular assays, this has been shown to increase mitochondrial biogenesis and enhance the sirtuin-mediated stress response, as documented in prominent metabolic research databases

[1] [2] Some patients report reduced symptoms within weeks of starting treatment, whilst others may require several months of consistent supplementation before noticing significant improvement

Remember that peptides are a relatively new area of research and clinical use, and the understanding of their safety and efficacy is continually evolving