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Optimizing the modified GPx-DTNB assay This study used the BoxBehnken design (BBD) and response surface modeling (RSM) (Haque et al

No serious adverse events were attributed to AOD-9604 across the entire clinical trial program involving over 900 participants

High levels of ROS, excessive inflammatory cells and cytokines in the wound microenvironment, insufficient new blood vessels, and weakened cell proliferation are the key factors that lead to the difficult healing of diabetic wounds 24

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