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In the STEP 1 trial with 1,961 participants, patients taking 2.4 mg semaglutide weekly alongside reduced caloric intake and increased physical activity lost an average of 14.9% of their body weight over 68 weeks

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Beyond-use window: a reconstituted vial is generally treated as usable for a limited number of weeks refrigerated track the reconstitution date and discard past the beyond-use window rather than pushing an old vial