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The Hollywood Reporter

2016;90:e1-e14 Martn-Fernndez J

L.OliveiraL

No liver toxicity was observed following a 3-day treatment with ribociclib, as indicated by the absence of detectable cell death at therapeutic concentrations up to the reported C max value in both patients, suggesting that ribociclib does not induce acute hepatotoxicity under short-term exposure conditions (Figure 11B)