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Nonetheless, the NGN2-iPSC-derived cortical neuron model provides a rapid, efficient, and reproducible and widely used system for investigating neuronal metabolism, compared with spontaneous differentiation or small moleculedriven differentiation, which require several weeks to months and often generate more heterogeneous populations [22, 93, 96,97,98,99]

GPx-1 also prevents oxidative stress by converting other free radicals, namely lipid peroxides, into less reactive molecules

It increases the availability of free fatty acids for energy, improving body composition even in calorie-controlled phases

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