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In the state of obesity, pro-inflammatory adipokines (such as leptin, resistin, etc.) directly promote inflammatory responses, and anti-inflammatory adipokines (such as adiponectin) are inhibited

"A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys." Science Translational Medicine 3.108 (2011): 108ra112

AST (Aspartate Aminotransferase) : Another enzyme that, like ALT, indicates liver damage when elevated

82 SA, a small-molecule HIF-1 inhibitor derived from natural marine products, has been recognized as a promising candidate for the development of anticancer medicines