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Description

We give 1/3 of this dose over the first 2 h and 2/3 of this dose over the next 3 h

In contrast, the M105I mutant maintains the hydrophobic loop (F27/F28 residues) in a consistently buried state throughout the simulations, failing to adopt the extended loop conformation characteristic of the WT structure

It was beneficial for PD when using ferroptosis inhibitor-iron chelator deferiprone for PD treatment in a randomized controlled trial (Moreau et al., 2018)