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A recent study using global metabolomic analysis in conjunction with metabolic tracer analysis suggested a distinctive function of DHODH in mitigating mitochondrial lipid peroxidation and thus ferroptosis, which was independent of its conventional role in producing pyrimidine nucleotides [21]

Mesenchymal Stem CellMacrophage Crosstalk Provides Specific Exosomal Cargo to Direct Immune Response Licensing of Macrophages during Inflammatory Responses

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Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats