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Finally, a recent 2021 study performed in a paediatric population (03 years) in Turkey found that a sublingual methyl-Cbl treatment regimen, comprising 1 mg daily replacement for a week followed by every other day for 2 weeks, 2 days/week for 2 weeks and once a week for 3 months was as effective as similar dose schedules of IM and oral CN-Cbl at normalising B12 levels (Orhan Kili et al., 2021)

Lowering the risk for cognitive issues tied to deficiency, such as difficulty focusing, poor memory and an increased risk for attention disorders

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This is preclinical data only, but it signals potential applications beyond fat metabolism that researchers have begun exploring