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Moreover, the present results suggested that sericin exhibited specific antitumor properties in TNBC cell lines, with no toxicity to the normal breast epithelial cell line MCF-10A, which was consistent with the findings from Kumar and Mandal (21), which indicated that sericin could not disrupt the cellular membrane integrity, and cause little toxicity in non-tumorigenic epithelial (MCF-10) cells and keratinocyte (HaCaT) cells

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The copper in GHK-CU has different uptake and distribution compared to free copper ions, as the peptide carrier helps cellular uptake and targets copper to specific cellular compartments