Safety concerns and effectiveness of long-term vitamin D and selenium use in endocrine disorders
As there were no specifically suitable positive control drugs for protective roles in PE, we chose the ferroptosis inhibitor Fer-1 as our option
Reported side effects are rare and typically mild temporary redness or irritation at the application site, usually resolving quickly No documented systemic toxicity in research literature at typical therapeutic doses European Medicines Agency and independent research groups rate it as well-tolerated Compatible with most standard skincare routines when used with appropriate spacing from incompatible actives Contraindications and cautions Known sensitivity or allergy to copper compounds: avoid use Active skin infections or open wounds at the injection site: delay treatment Pregnancy and breastfeeding: insufficient safety data
Disclosures: Alejandra Paredes-Marin: Nothing to Disclose, Julia Napoli: Nothing to Disclose, Vikram Sivakumar: Nothing to Disclose, Christian Near: Nothing to Disclose, Dakota Trick: Nothing to Disclose, Helen Adams: Nothing to Disclose, Alyson Harty: Nothing to Disclose, Ritu Agarwal: Nothing to Disclose, Douglas Dieterich: Gilead: Consultant, madrigal: Speaking and Teaching, John Bucuvalas: Mirum Pharmaceutical: consultant, Madrigal Pharmaceutical: Consultant, Neurogene: Consultant, Iecure: Consultant, Tatyana Kushner: Gilead: Grant/Research Support, Gilead: Advisor, GSK: Advisor, Eiger: Advisor, Jaime Chu: Albireo: Consultant, Swati Antala: Nothing to Disclose, Asher Leviton: Nothing to Disclose, Augusto Villanueva: Nothing to Disclose, Scott Friedman: 89 Bio: Consultant, Boehringer Ingelheim: Consultant, Boston Pharmaceutical: Consultant, Bristol Myers Squibb: Consultant, Merck: Consultant, Glycotest: Consultant, Morphic Therapeutics: Consultant, HepGene: Consultant, North Sea Therapeutics: Consultant, Pfizer Pharmaceuticals: Consultant, Sagimet: Consultant, Scholar Rock: Consultant, Prosciento: Consultant, Seal Rock: Consultant, Surrozen: Consultant, Takeda Pharmaceuticals: Consultant, Rachel Smith: Nothing to Disclose, Xiaotao Zhang: Nothing to Disclose, Meena Bansal: Nothing to Disclose, Nothing to Disclose, Nothing to Disclose, Nothing to Disclose, Nothing to Disclose, Nothing to Disclose, Nothing to Disclose, Nothing to Disclose, Nothing to Disclose, Nothing to Disclose, Nothing to Disclose 1189 CLINICAL, PSYCHOSOCIAL AND SOCIAL DETERMINANTS OF HEALTH FACTORS ASSOCIATED WITH DEGREE OF HEPATIC STEATOSIS AND LIVER STIFFNESS AMONG OVERWEIGHT AND OBESE ADULTS AT RISK OF METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE Monica Tincopa 1 Lisa Richards 1 Rohit Loomba 1 , 1 University of California, San Diego Background: The severity of metabolic dysfunction-associated steatotic liver disease (MASLD) among patients with overweight and obesity is heterogeneous and may be moderated by behavioral, psychosocial and social determinant of health (SDOH) factors
