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Treatment of essential arterial hypertension with enalapril does not result in normalization of endothelial dysfunction of the conduit arteries

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Curcumin suppresses constitutive activation of AP-1 by downregulation of JunD protein in HTLV-1-infected T-cell lines (Retraction of vol 30 pg 313 2006) Leukemia Res

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Animal studies demonstrate that chronic tesofensine treatment produces sustained weight loss even as tolerance to the hypophagic effect gradually develops, indicating additional factors beyond appetite regulation contribute to maintaining maximal weight loss

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Tofacitinib also significantly inhibits IL-22-induced CXCL1 and CXCL5 expression in human colonic tissues, suggesting that targeting the IL-22/CXC chemokine axis through JAK/STAT inhibition may be a viable therapeutic strategy

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